If you lost your job due to Layoff, re-organization, downsizing or whatever your employer called it, chances are that you are qualified to receive Unemployment Benefits. If you quit your job, chances are good that you do not qualify to receive benefits.
Not One Place to File
Unfortunately, the states control the distribution of benefits. And, each state's process is at least a little different than all the others. So, there is not just ONE online site where you can visit to apply for benefits. There are at least 51 - counting the District of Columbia and the states. There may also be separate sites for U.S. possessions or territories like Puerto Rico.
You can also generally apply for benefits by appearing in person at one of your State's Unemployment offices and some states may permit you to file by phone.
General Rule
Before you file, find out the options in your state. And, see the Menu item (below) about WHERE to file. The question of WHERE (i.e., in which state) is critical so you don't waste time filing in the wrong state.
If you have the opportunity, check with others in your state who have already applied and they may be able to give you some tips.
Follow-up
We'll deal with this separately. But, for now, keep in mind that the process does not stop simply because you've filed a request for Unemployment Benefits.